Publication Repository

MARINE BIODIVERSITY AS A SOURCE OF CHEMICAL DIVERSITY

Show simple item record

dc.contributor Australian Inst Marine Sci
dc.contributor Australian Institute Of Marine Science
dc.contributor Australian Institute Of Marine Science (aims) en
dc.contributor.author HALL, MR
dc.contributor.author DEVRIES, DJ
dc.date.accessioned 2013-02-28T06:46:34Z
dc.date.accessioned 2017-03-21T00:52:50Z
dc.date.accessioned 2017-03-21T00:52:50Z
dc.date.accessioned 2019-07-08T02:18:57Z
dc.date.available 2013-02-28T06:46:34Z
dc.date.available 2017-03-21T00:52:50Z
dc.date.available 2017-03-21T00:52:50Z
dc.date.available 2019-07-08T02:18:57Z
dc.date.issued 1994-10-01
dc.identifier 1547 en
dc.identifier.citation De Vries DJ and Hall MR (1994) Marine biodiversity as a source of chemical diversity. Drug Development Research. 33: 161-173. en
dc.identifier.issn 0272-4391
dc.identifier.uri http://epubs.aims.gov.au/11068/1547
dc.description.abstract Total global biodiversity is estimated at between 3 and 500 x 10(6) species of prokaryote and eukaryote organisms spread across 70 or more phyla. the marine macrofauna alone are estimated between 0.5 and 30 x 10(6) species and represents a broader range of taxonomic diversity than that found in the terrestrial environment, which has been the traditional source of natural products. With a typical eukaryote possessing 50,000 genes, the global marine macrofauna are the source of 2.5 x 10(10) to 1.5 x 10(12) primary products and an associated extensive range of secondary products. However, only a few thousand novel compounds from marine organisms have been described. These compounds have proven unique in chemical and pharmacological terms but, as yet, not therapeutic agents have resulted. Given a broader drug discovery strategy, and facilitated by technological advances, it si predicted that the characterisation of marine chemical diversity will be accelerated. Strategies fro drug discovery from the virtually untapped chemical diversity of marine organisms are discussed. (C) 1994 Wiley-Liss, Inc.
dc.language English
dc.language en en
dc.relation.ispartof Drug Development Research - pages: 33: 161-173 en
dc.relation.ispartof Null
dc.subject Biological Products
dc.subject Vents
dc.subject Ecology
dc.subject Chemistry, Medicinal
dc.subject Marine Biology
dc.subject Conservation
dc.subject Sponge
dc.subject Receptor
dc.subject Anti-neoplastic Agents
dc.subject Pharmacology & Pharmacy
dc.subject Sea
dc.subject Peptides
dc.subject Natural-products
dc.subject Pharmacognosy
dc.subject Metabolites
dc.title MARINE BIODIVERSITY AS A SOURCE OF CHEMICAL DIVERSITY
dc.type journal article en
dc.identifier.wos WOS:A1994QF97100012


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search Publication


Browse

My Account