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Acetylated sesterterpenes from the Great Barrier Reef sponge Luffariella variabilis

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dc.contributor Sch Marine Biol & Aquaculture
dc.contributor James Cook Univ N Queensland
dc.contributor Aims&jcu
dc.contributor James Cook University
dc.contributor Australian Inst Marine Sci
dc.contributor Australian Institute Of Marine Science
dc.contributor Australian Institute Of Marine Science (aims) en
dc.contributor.author TAPIOLAS, DIANNE M.
dc.contributor.author ETTINGER-EPSTEIN, PIERS
dc.contributor.author MOTTI, CHERIE A.
dc.contributor.author DE NYS, ROCKY
dc.contributor.author WRIGHT, ANTHONY D.
dc.contributor.author BATTERSHILL, CHRISTOPHER N.
dc.date.accessioned 2013-02-28T06:45:36Z
dc.date.accessioned 2017-03-21T00:56:35Z
dc.date.accessioned 2017-03-21T00:56:35Z
dc.date.accessioned 2019-05-09T01:12:10Z
dc.date.available 2013-02-28T06:45:36Z
dc.date.available 2017-03-21T00:56:35Z
dc.date.available 2017-03-21T00:56:35Z
dc.date.available 2019-05-09T01:12:10Z
dc.date.issued 2007-04-01
dc.identifier 7249 en
dc.identifier.citation Ettinger-Epstein P, Motti CA, de Nys R, Wright AD, Battershill CN and Tapiolas DM (2007) New acetylated sesterterpenes from the Great Barrier Reef sponge Luffariella variabilis. Journal of Natural Products. 70:648-651. en
dc.identifier.issn 0163-3864
dc.identifier.uri http://epubs.aims.gov.au/11068/7249
dc.description Link to abstract/full text - http://dx.doi.org/10.1021/np060240d en
dc.description.abstract Chemical investigation of the sponge Luffariella variabilis collected from the Palm Island group of the Great Barrier Reef, Australia, yielded three new acetylated compounds, 25-acetoxyluffariellin A (1), 25-acetoxyluffariellin B (2), and 25-acetoxyseco-manoalide (3). The structures of the new compounds were elucidated on the basis of interpretation of their spectroscopic data. The known metabolites manoalide (4), seco-manoalide (5), luffariellin A (8), and manoalide monoacetate (10) were also isolated. The new acetylated compounds (1-3) were labile in the sponge tissue when samples were allowed to thaw prior to extraction, but were stable once isolated. Sponge samples that were completely thawed contained only hydroxylated compounds (alcohols). This finding supported the deduction that the acetylated compounds are being enzymatically transformed and/or degraded.
dc.description.uri http://dx.doi.org/10.1021/np060240d en
dc.language English
dc.language en en
dc.relation.ispartof Null
dc.relation.ispartof Journal of Natural Products - pages: 70:648-651 en
dc.subject Plant Sciences
dc.subject Chemistry, Medicinal
dc.subject Pharmacology & Pharmacy
dc.title Acetylated sesterterpenes from the Great Barrier Reef sponge Luffariella variabilis
dc.type journal article en
dc.identifier.doi 10.1021/np060240d
dc.identifier.wos WOS:000246007200029


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